Ipamorelin vs Sermorelin
Ipamorelin is a pentapeptide GH secretagogue / GHSR-1a agonist. Sermorelin is a growth hormone-releasing hormone (GHRH) analog; N-terminal 29-amino-acid fragment of human GHRH. They are different materials with different identities and different research literatures; the table below sets the two identities side by side, the sections after it summarise what each is studied for, and the certificate rows show how each has tested.
Ipamorelin and Sermorelin side by side
| Field | Ipamorelin | Sermorelin |
|---|---|---|
| Catalogue name | Ipamorelin | Sermorelin |
| Type | Single peptide | Single peptide |
| Class | Pentapeptide GH secretagogue / GHSR-1a agonist | Growth hormone-releasing hormone (GHRH) analog; N-terminal 29-amino-acid fragment of human GHRH |
| Components | Single compound | Single compound |
| Molecular formula | C38H49N9O5 | C149H246N44O42S |
| Molecular weight | 711.85 Da | 3357.93 Da |
| Sequence length | 5 residues | 29 residues |
| CAS or identifier | 170851-70-4 | 86168-78-7 |
| Form supplied | Lyophilized powder | Lyophilized powder |
| Sizes | 10mg | 10mg |
| Price from | $70 | $85 |
| Documented HPLC results | 4 (99.51 to 99.98%) | 5 (99.03 to 99.84%) |
| Testing laboratories | Freedom Diagnostics | Accurate Test Labs, Freedom Diagnostics |
Identity fields come from the catalogue entry for each compound. Certificate counts are documented third-party HPLC results with a published certificate; image-only documents are excluded from the counts.
What the research literature describes
Ipamorelin
- Ghrelin Receptor Activation GHSR-1a Agonist
- No Cortisol or Prolactin Elevation Selectivity
- Physiologic GH Secretion Pattern Pulsatile GH
Sermorelin
- GHRH Receptor Agonism GHRH-R
- Downstream IGF-1 Signaling GH → IGF-1
- Preserved Physiologic Rhythm Feedback
- Upstream, Not Exogenous Upstream
- Short Plasma Half-Life Half-Life
- GHRH(1-29) Active Fragment Sequence
What each is studied for
Ipamorelin
- Selective GH Secretagogue Endocrinology
- GH Secretion & Sleep Sleep Research
- Bone Growth Models Musculoskeletal
- Synergy with GHRH Analogs Combination Research
Sermorelin
- Growth Hormone Axis Endocrine
- Body Composition Models Body Composition
- Slow-Wave Sleep Sleep Architecture
- Somatopause Aging Research
Headings name the mechanisms and research applications described for each compound; the full text of each sits on the compound monograph linked below. They summarise findings reported in preclinical models. They describe what has been studied, not outcomes in people or animals outside the laboratory.
Catalogue, monographs and certificates
- Ipamorelin in the catalogueSizes, price and current certificate
- Ipamorelin monographMolecular data and mechanisms studied
- Ipamorelin lab resultsEvery third-party certificate
- Sermorelin in the catalogueSizes, price and current certificate
- Sermorelin monographMolecular data and mechanisms studied
- Sermorelin lab resultsEvery third-party certificate
- All comparisonsEvery pair in the library
What is the difference between Ipamorelin and Sermorelin?
Ipamorelin is a pentapeptide GH secretagogue / GHSR-1a agonist; Sermorelin is a growth hormone-releasing hormone (GHRH) analog; N-terminal 29-amino-acid fragment of human GHRH. Ipamorelin has 5 residues and Sermorelin has 29. Their molecular identities, the models they have been studied in and their certificate records are all listed on this page.
Are Ipamorelin and Sermorelin sold together?
No. Eon Peptides lists them as separate catalogue items, each with its own sizes and its own certificates.
How has each tested?
Ipamorelin: 4 documented third-party HPLC results from 99.51% to 99.98%. Sermorelin: 5 documented results from 99.03% to 99.84%. Every certificate is published and linked from each compound's lab results page.
Which one should a research project use?
That depends on the pathway and model under study, which is a scientific question this page does not answer. What it does is put the identities, the described mechanisms and the analytical records side by side so the choice can be made on documented facts. Both materials are for laboratory research use only.
For research use only. Not for human or veterinary use. Nothing on this page describes or recommends use in people or animals.