Every lot of Melanotan I is tested by an independent ISO/IEC 17025-accredited lab in the USA. 99%+ purity isn't a target here. It's the requirement.
Don't take our word for it: test any vial at an accredited lab of your choice. If HPLC purity comes back under 99%, we refund your order and pay for the test.
Melanotan I is a linear analog of α-melanocyte-stimulating hormone studied for melanocortin-receptor binding, with MC1R the principal characterised target. It is the linear counterpart to the cyclic Melanotan II, and is studied in pigmentation and melanocortin-signalling research. For laboratory research use only.
Linear α-MSH analog studied at melanocortin receptors
The numbers that define Melanotan I and how it is being studied. For laboratory research use only.
MC1R
Principal Target
Melanocortin-1 receptor
5 mg
Per Vial
Lyophilized powder
Linear
Structure
Counterpart to cyclic Melanotan II
3
Research Areas
Pigmentation
Melanocortin signalling
How It Works
How Melanotan I works
The pathways Melanotan I acts on - and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
Melanocortin Receptor Binding
Receptor
Melanotan I is characterised as an α-MSH analog binding the melanocortin receptor family, with MC1R the principal studied target in pigmentation research.
MC1R engagement
α-MSH analog
Melanocortin receptor family
Melanogenesis Endpoints
Cellular
Melanin synthesis in melanocyte culture is the standard measured endpoint in the published MC1R literature.
Melanocyte culture models
Melanin synthesis endpoints
Dose-response characterisation
Linear vs Cyclic
Structure
Melanotan I is linear where Melanotan II is cyclic. The structural difference is associated with differing receptor-selectivity profiles across the melanocortin family.
Linear backbone
Differing selectivity profile
Studied alongside Melanotan II
Uses & Applications
What Melanotan I is researched for
The main areas Melanotan I is being studied for - and the study-reported figures behind them.
Dermatology
Pigmentation Models
Melanin synthesis in melanocyte culture is the principal studied endpoint.
Endocrinology
Melanocortin Signalling
Studied as an α-MSH analog across the melanocortin receptor family.
Methods
Comparative Work
Frequently studied alongside the cyclic analog Melanotan II for selectivity comparison.
Analytical
Reference Material
Used as a characterised melanocortin-agonist reference in assay development.
Study-reported magnitudes
Representative figures from published research. Bars fill as you scroll.
MC1R BindingCharacterised
Melanogenesis EndpointsMeasured
Receptor Selectivity ProfileCharacterised
Documented Purity≥99%
Figures are representative of published research findings and shown for reference.
Molecular Structure
The Melanotan I molecule
An interactive 3D model rendered from the compound record - rotate and explore its structure.
Molecular model
Sequence length
13 residues
Physical form
Lyophilized powder
Documented purity
≥99% by HPLC
Compound Information
Full specification
Chemical Name
Melanotan I (α-MSH analog)
Content
5 mg per vial
Principal Target
Melanocortin-1 receptor (MC1R)
Structure
Linear analog (cf. cyclic Melanotan II)
Form
Lyophilized powder
Purity
≥99% by HPLC
Appearance
White to off-white powder
Solubility
Water-soluble
Storage
-20°C, protected from light
Classification
Research use only
FAQ
Common questions about Melanotan I
Melanotan I is linear; Melanotan II is cyclic. The structural difference is associated with differing selectivity across the melanocortin receptor family. Both are studied in melanocortin research.
The melanocortin-1 receptor (MC1R), characterised in pigmentation research using melanocyte culture models.
The molecular weight will be published here from the lot's Certificate of Analysis rather than quoted from a secondary source.
Each lot is analysed by reverse-phase HPLC and released at ≥99%, with a Certificate of Analysis.
Store lyophilized at -20°C for long-term stability, protected from light and moisture, and avoid repeated freeze-thaw cycles.
Research Use Only.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
