Every lot of MOTS-c / SS-31 is tested by an independent ISO/IEC 17025-accredited lab in the USA. 99%+ purity isn't a target here. It's the requirement.
Don't take our word for it: test any vial at an accredited lab of your choice. If HPLC purity comes back under 99%, we refund your order and pay for the test.
This is a blend. MOTS-c and SS-31 are combined in a single 20 mg vial, 10 mg of each. Both are mitochondria-associated research peptides approached from different angles: MOTS-c is mitochondrial-derived and studied for AMPK signalling and metabolic regulation, while SS-31 is a cardiolipin-targeting peptide studied for inner-membrane stabilisation. The combination has not been characterised as a single formulation.
The numbers that define MOTS-c / SS-31 and how it is being studied. For laboratory research use only.
2
Research Peptides
MOTS-c · SS-31
20 mg
Total Per Vial
10 mg of each component
AMPK
MOTS-c Pathway
Metabolic regulator
4
Research Areas
Mitochondrial function
Metabolic regulation
Oxidative stress
How It Works
How MOTS-c / SS-31 works
The pathways MOTS-c / SS-31 acts on - and what each one does. The animation traces its signal outward from the compound to every target it engages.
Signalling pathways studied in preclinical models · illustrative
AMPK Signalling
MOTS-c
MOTS-c is a mitochondrial-derived peptide encoded in the mitochondrial genome. AMPK pathway activation and metabolic-regulation endpoints are the characterised readouts.
Mitochondrial-derived peptide
AMPK pathway activation
Metabolic regulation endpoints
Cardiolipin Binding
SS-31
SS-31 binds cardiolipin on the inner mitochondrial membrane. Membrane stabilisation and preserved cristae architecture are the characterised endpoints, alongside reduced reactive oxygen species.
Cardiolipin binding
Inner-membrane stabilisation
Reactive oxygen species endpoints
Two Mitochondrial Angles
Combined
The vial pairs a signalling-side peptide with a membrane-side peptide. The two are characterised separately and no interaction data exists for the pair.
Signalling and membrane arms
Matched handling
Interaction not characterised
Uses & Applications
What MOTS-c / SS-31 is researched for
The main areas MOTS-c / SS-31 is being studied for - and the study-reported figures behind them.
Cell Biology
Mitochondrial Function
Both peptides are studied for mitochondrial function from different mechanistic angles.
Metabolic
Metabolic Regulation
MOTS-c is characterised for AMPK-pathway activation in metabolic models.
Cell Biology
Oxidative Stress Models
SS-31 is studied for reactive-oxygen-species endpoints and membrane integrity.
Methods
Parallel Protocols
One vial holds both peptides under matched handling.
Study-reported magnitudes
Representative figures from published research. Bars fill as you scroll.
MOTS-c AMPK ActivationCharacterised
SS-31 Cardiolipin BindingCharacterised
Oxidative Stress EndpointsMeasured
Blend Interaction DataNone
Figures are representative of published research findings and shown for reference.
Molecular Structure
The MOTS-c / SS-31 molecule
An interactive 3D model rendered from the compound record - rotate and explore its structure.
Molecular model
Sequence length
blend
Physical form
Lyophilized powder blend
Documented purity
≥99% by HPLC
Compound Information
Full specification
Components
MOTS-c + SS-31
Content
20 mg per vial (10 mg of each component)
MOTS-C
16-amino acid mitochondrial-derived peptide
SS-31
Cardiolipin-targeting tetrapeptide
Form
Lyophilized powder blend
Purity
≥99% by HPLC
Appearance
White to off-white powder
Solubility
Water-soluble
Storage
-20°C, protected from light
Classification
Research use only
FAQ
Common questions about MOTS-c / SS-31
They approach mitochondrial research from different angles: MOTS-c through AMPK signalling, SS-31 through cardiolipin binding and inner-membrane stabilisation. One vial holds both under matched handling.
No. Each peptide is characterised separately and no interaction data exists for the pair.
The separate products let you control each peptide's quantity independently and are offered in 10, 30 and 50 mg. This vial fixes the ratio at 10 mg and 10 mg.
Each lot is analysed by reverse-phase HPLC and released at ≥99%, with a Certificate of Analysis.
Store lyophilized at -20°C for long-term stability, protected from light and moisture, and avoid repeated freeze-thaw cycles.
Research Use Only.
Not for human or veterinary use. For in-vitro laboratory research only. These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease. Sold exclusively to qualified researchers and institutions.
